FDA

US FDA Pharma GMP 21 CFR 211

Esta certificación beneficiará  a los fabricantes de productos sujetos a ls requerimientos regulatorios de FDA para evitar “findings” en las inspecciones de la citada Agencia. Excelente cualificación para los profesionales de Quality Asurance, Manufacturing, Regulatory Affairs, Supplier Quality and Quality Control  de empresas dedicadas a la fabricación de  productos farmacéuticos.

Nuestro director es:

José Rodríguez

Nuestro director es:

Biólogo y doctor en Inmunología por la Universidad de Granada. Es Presidente y CEO de Business Excellence Consulting (BEC), empresa de consultoría y formación en Regulatory compliance, Risk management y Operational Excellence en los sectores regulados por la FDA.

Carretera de Fuencarral, Km 22 Edificio Net-Pharma 28108 Alcobendas (Madrid)

Programa

Opening Remarks
U.S. FDA Overview

FDA Laws and Regulations


FDA Guides and Guidances

21 CFR Part 211
Subpart A-General Provisions

211.1 – Scope

Subpart B-Organization and Personnel

211.22 – Responsibilities of quality control unit


211.25 – Personnel qualifications


211.28 – Personnel responsibilities


211.34 – Consultants.

Subpart C-Buildings and Facilities

211.42 – Design and construction features


211.44 – Lighting


211.46 – Ventilation, air filtration, air heating and cooling


211.48 – Plumbing


211.50 – Sewage and refuse


211.52 – Washing and toilet facilities


211.56 – Sanitation


211.58 – Maintenance

Subpart D-Equipment

211.63 – Equipment design, size, and location


211.65 – Equipment construction


211.67 – Equipment cleaning and maintenance


211.68 – Automatic, mechanical, and electronic equipment


211.72 – Filters

Subpart E-Control of Components and Drug Product Containers and Closures

211.80 – General requirements


211.82 – Receipt and storage of untested components, drug product containers, and closures


211.84 – Testing and approval or rejection of components, drug product containers, and closures


211.86 – Use of approved components, drug product containers, and closures


211.87 – Retesting of approved components, drug product containers, and closures


211.89 – Rejected components, drug product containers, and closures


211.94 – Drug product containers and closures

Subpart F-Production and Process Controls

211.100 – Written procedures; deviations


211.101 – Charge-in of components


211.103 – Calculation of yield


211.105 – Equipment identification


211.110 – Sampling and testing of in-process materials and drug products


211.111 – Time limitations on production


211.113 – Control of microbiological contamination


211.115 – Reprocessing

Subpart G-Packaging and Labeling Control

211.122 – Materials examination and usage criteria


211.125 – Labeling issuance


211.130 – Packaging and labeling operations


211.132 – Tamper-evident packaging requirements for  over-the-counter (OTC) human drug products


211.134 – Drug product inspection


211.137 – Expiration dating

Subpart H-Holding and Distribution

211.142 – Warehousing procedures


211.150 – Distribution procedures

Subpart I-Laboratory Controls

211.160 – General requirements


211.165 – Testing and release for distribution


211.166 – Stability testing


211.167 – Special testing requirements


211.170 – Reserve samples


211.173 – Laboratory animals


211.176 – Penicillin contamination

Subpart J-Records and Reports

211.180 – General requirements


211.182 – Equipment cleaning and use log


211.184 – Component, drug product container, closure, and labeling records


211.186 – Master production and control records


211.188 – Batch production and control records


211.192 – Production record review


211.194 – Laboratory records


211.196 – Distribution records


211.198 – Complaint files

Subpart K-Returned and Salvaged Drug Products

211.204 – Returned drug products


211.208 – Drug product salvaging

Profesores

José (Pepe) Rodríguez

Biólogo y doctor en Inmunología por la Universidad de Granada. Es Presidente y CEO de Business Excellence Consulting (BEC), empresa de consultoría y formación en Regulatory compliance, Risk management y Operational Excellence en los sectores regulados por la FDA. BEC Spain es una empresa filial en España de BEC.

Entre 2009 y 2011 fue Science Advisor para la U.S. FDA en el distrito de San Juan (Puerto Rico).

Está certificado como Quality Manager, Quality Engineer, Quality Auditor, Quality HACCP Auditor, Biomedical Auditor, Six Sigma Black Belt, and GMP Professional por la American Society of Quality (ASQ). Miembro y Presidente de la ASQ en Puerto Rico entre 2003 y 2005. Es miembro de RAPS, AAMI, y PDA.

Es autor de los siguientes libros:

  • CAPA for the fda regulated industry (2010)
  • Quality risk management in the fda regulated industry (2012)
  • The fda and worldwide current good manufacturing practices and quality system requirements guidebook for finished pharmaceuticals (2014)
  • Handbook of investigation and effective capa systems (2016)

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